AI/ML Scientist

Who We Are & What We Do

At Helix, our mission is simple: to help everyone improve their lives through their DNA.

Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics. What is special about this role?

Helix maintains one of the largest linked genomic and clinical datasets in the United States. Helix's Data Science & AI team innovates and develops state-of-the-art models that leverage this clinicogenomic dataset, for example, germline genomes linked to longitudinal clinical records, to better understand and predict a patient's journey, taking precision medicine to a new level.

You will take ownership of impactful work early on; your results will be influential, and you will collaborate closely with domain experts. You will have direct access to data that most professionals in this field only read about, along with the opportunity to develop a deep understanding of genomic and clinical data alongside senior experts who have dedicated their careers to this work. Work you would touch in the first year:

• Training and evaluating generative models on longitudinal clinical records fused with variant-level germline genomics, to forecast disease onset and patient trajectory
• Building and measuring LLM agentic solutions that pull structured findings out of clinical text and the published literature
• Contributing to our multi-agent pipeline for clinical variant interpretation, which is in production today and used by our clinical genomics team on every uncurated variant
• Feature and representation work on genomic data: turning variant and gene-level information into something a model can actually use
• Running experiments carefully eno